PhotonIcs and Electromagnetics Research Symposium,
also known as Progress In Electromagnetics Research Symposium
PIERS Proceedings
Published: 2015-07-09
Spontaneous Hemodynamic Activity in Prefrontal Cortex of Depression Patients Assessed with Functional Near-infrared Spectroscopy
By
Proceedings of 2015 Photonics & Electromagnetics Research Symposium, Prague, July 6 - 9,Page(s)1853-1857
Abstract
Patients with major depressive disorder (MDD) typically suffered from pervasive depressed mood or anhedonia, accompanied by several cognitive and physical symptoms. In this study, functional near-infrared spectroscopy (fNIRS) was applied to investigate the spontaneous activity of hemodynamic in the prefrontal cortex (PFC) of the brain. 21 patients with MDD (including 12 with antidepressant and 9 without medication) participated in 8-min resting state measurement. By analyzing the interhemispheric correlation and the correlation maps of the PFC, our results indicated that patients with MDD showed significantly reduced interhemispheric correlation in the PFC and disrupted cortical organizations in the PFC. This study showed that fNIRS could be an effective and convenient way to assess neural features of depression.
Citation
Tingting Cai, Sailing He, Xinge Li, Jiangxue Li, Hongjun Peng, Jie Xu, and Huilin Zhu, "Spontaneous Hemodynamic Activity in Prefrontal Cortex of Depression Patients Assessed with Functional Near-infrared Spectroscopy," Proceedings of 2015 Photonics & Electromagnetics Research Symposium, Prague, July 6 - 9,Page(s)1853-1857
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