Active electrode is considered an extremely effective structure for capturing hu- man bio-potential signals when compared with the traditional Ag/AgCl electrodes. This work presents a new configuration for a double ended active electrode included in a System-in-Package (SiP) solution. The chip overcomes the traditional problems of relatively large area and slow time response, and it demonstrates the characteristics of low power consumption, DC and 50 Hz rejection. It has a 2.1 kHz bandwidth with a 40 dB gain, and it reaches the extremely low cut-off frequency of 7.9 MHz. The working voltage is 1.8 V, and the power consumption of per channel is 6.7 µW. This chip has been fabricated with 0.18 µm 1P6M CMOS Process and then inserted in a SiP.